הכנס השנתי השביעי של האגודה הישראלית לחקר השליה

Placental Stress: Adaptation or Maladaptation

מכון וייצמן: אודיטוריום בוטנאר, בניין בלפר
ביום רביעי  29.11.2016 , כ"ט בחשון, תשע"ו

 תכנית הכינוס:

08:00  התכנסות ורישום

08:20-08:30  דברי פתיחה: פרופ' סורינה גריסרו- גרנובסקי,  יו"ר החברה הישראלית לחקר השליה

08:30-09:15  מושב הצגת עבודות א' – הצגת 3 עבודות
יו"ר: ד"ר טל בירון-שנטל, ד"ר טל  רז


 Oded Komemi1,4, Gali Epstein Shochet1,4 , Meir Pomeranz2,4, Ami Fishman2,4, Liat Drucker1,4, Shelly Tartakover Matalon1,4,Michael Lishner1,3,4

Oncogenetic Laboratory1, Department of Obstetrics & Gynecology2, and Internal Medicine A3, Meir Medical Center Kfar-Saba affiliated with Sackler Faculty of Medicine, Tel-Aviv University4, Israel.

Placental conditioned extracellular matrix (ECM) prevents breast cancer cells attachment and activities their survival mechanisms: a key for future distant metastases 

Ariel1, D. Goldman-Wohl2, E. Gazit3, R. Loewenthal3 , S. Yagel21 The Perinatal Pathology Unit, the Department of Pathology, and the 2Center for Human Placenta Research, the Department of Obstetrics and Gynecology, Hadasssah-Hebrew University Medical Center, Mount Scopus, Jerusalem, 3The Laboratory for Tissue typing, Chaim Sheba Medical Center, Tel Hashomer, Israel
Triple paternal contribution to a normal/complete molar chimeric singleton placenta

Michal Bar1,4, Shelly Tartakover Matalon1,4, Meir Pomeranz2,4, Ami Fishman2,4, Liat Drucker1,4, Michael Lishner1,3,4 Oncogenetic Laboratory1, Department of Obstetrics & Gynecology2, and Internal Medicine A3, Meir Medical Center Kfar-Saba affiliated with Sackler Faculty of Medicine, Tel-Aviv University4, Israel                

Placental soluble factors’ effect on the metastatic potential of breast cancer cells

 09:15-10:00    הרצאת אורח       Prof. Alon Chen

Head,  Department of  Neurobiology, Weizmann Institute of Science, Israel  
Director, Department of Stress Neurobiology & Neurogenetics, Max Planck Institute of Psychiatry, Germany 

The role of placenta in mediating the effects of prenatal stress on fetal programming and adult susceptibility to psychiatric disorders              


 10:00-10:15 הפסקת קפה

10:15-11:45  מושב הצגת עבודות ב'- הצגת 6 עבודות 
יו"ר: ד"ר דבורה  וואהל, פרופ' מ. עופר פאינרו


Ohad Gluck 1, Yossi Mizrachi 1 Adi Marciano1, Letizia Schreiber2, Jacob Bar 1, Michal Kovo 1 Departments of Obstetrics and Gynecology1, and Pathology2, E. Wolfson Medical Center, Holon, affiliated with Sackler School of Medicine, Tel Aviv University, Israel 
Pregnancy, neonatal outcome and placental pathology in relation to the severity of fetal growth
restriction
 

Keren Rotshenker-Olshinka1, Sveta Terlezky1, Letizia Schreiber2, Rivka Farkash1, Arnon Samueloff1 and Sorina Grisaru –Granovsky1 

Department of Obstetrics and Gynecology, Shaare Zedek Medical Centre, affiliated with the Hebrew University, Jerusalem, Israel  2 Department of Pathology, Edith Wolfson Medical Center, Holon, Israel   affiliated with Sackler School of Medicine, Tel Aviv University        

Recurrent intrauterine growth restriction (r IUGR): is the placenta pathology the key to the conundrum?Noa Mevorach-Zussman1, Nizr Khatib2, Yuval Ginsberg2, Zeev Weiner2, Jacob Bar1, Ron Beloosesky2, Michal Kovo1

Department of Obstetrics & Gynecology, Edith Wolfson Medical Center, Holon, affiliated with Sackler Faculty of Medicine, Tel Aviv University, Israel and 2 Department of Obstetrics & Gynecology, Rambam Medical Center, Haifa, Israel

Mechanism of maternal magnesium sulfate neuroprotection may be mediated via placental ACTH and inflammatory cascade: using the dual-perfused human single cotyledon model 

Lysenko M, Noam BE, Biton EI, Garbow JR, Neeman M

Department of Biological Regulation, The Weizmann Institute of Science, Rehovot, Israel                   

Characterization of Biotin Transport in the Murine Placenta by DCE-MRI

Ohad Feldstein1, Eran Weiner1, Letizia Schreiber 2, Ehud Grinstein1,  Elad Barber1, Ann Dekalo1, Jacob Bar 1, Michal Kovo1

Departments of Obstetrics & Gynecology1 and Pathology2, the Edith Wolfson Medical Center, Holon, Israel affiliated with Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel 
The differences in placental component and obstetric outcome of twins versus singleton pregnancies complicated by preeclampsia

Ron Beloosesky,  Nizar Khatib,  Yuval Ginsberg, Zeev Weiner
Department of Obstetrics and Gynecology, Rambam Medical Center, Haifa, Israel

Placental-mediated inhibition of inflammation, apopotosis and oxidative stress by maternal magnesium sulphate in response to lipopolysaccharide in late gestation: a potential mechanism for Mg neuroprotective effect


 11:45-12:15  הפסקת צהריים

12:15-13:30   מושב הצגת עבודות ג'- הצגת 5 עבודות
יו"ר: ד"ר מיכל קובו, פרופ' מ. רון בלוססקי


 Sivan Farladansky-Gershnabel1, Hilah Gal2, Dvora Kidron1, Valery Krizhanovsky2,  Tal Biron-Shental1

1Meir Medical Center, affiliated with Tel Aviv University, Israel; 2Department of Molecular Cell Biology, The Weizmann Institute of Science, Rehovot, Israel 
Telomere homeostasis and senescence markers are differently expressed in placentas from pregnancies with early versus late onset preeclampsia
 

Debra Goldman-Wohl1, Caryn Greenfield1, Iris Eisenberg1, Galia Skarzinsky2, Tal Imbar1, Ronit Haimov-Kochman1, Amina Jbara3, Polina Denichenko3, Rotem Karni 3, Ilana Ariel2 and Simcha Yagel1.

1Magda and Richard Hoffman Center for Placenta Research, Obstetrics and Gynecology, 2Pathology, 3Biochemistry and Molecular Biology, IMRIC, Hebrew University-Hadassah Medical School, Jerusalem, Israel.

Defining the role of alternative splicing regulation in trophoblast differentiation: implications for maternal and fetal health 

Elad Barber, Eran Weiner, Ohad Feldstein, Ann Dekalo, Letizia Schreiber, Jacob Bar, Michal Kovo

Department of Obstetrics & Gynecology1 and Pathology2, the Edith Wolfson Medical Center, Holon, affiliated with Sackler School of Medicine, Tel Aviv University Israel 
Placental pathology and umbilical cord abnormalities in bichorionic vs. monochorionic twin pregnancies 

Shani S. Swissa1, Reli Hershkovitz2, Irit Szaingurten-Solodkin3, Asnat Walfisch2, Shimrit Yaniv-Salem2 and Ofer Beharier2,3

1The Shraga Segal Department of Microbiology and Immunology, 2Department of Obstetrics and Gynecology, Soroka University Medical Center, 3Department of Physiology and Cell Biology, Ben-Gurion University of the Negev, Beer Sheva, Israel.

Predictive role of maternal angiogenic biomarkers in future adverse perinatral outcome in intrauterine growth restriction pregnancies 

Ann Dekalo1, Eran Weiner1, Ohad Feldstein1, Elad Barber1, Letizia Schreiber2, Jacob Bar1, Michal Kovo1

Department of Obstetrics & Gynecology1 and Pathology2, the Edith Wolfson Medical Center, Holon, Israel, affiliated with Sackler School of Medicine, Tel Aviv University, Israel 
The placental factor in spontaneous preterm delivery in twins vs. singletons pregnancies